Prime Medicine, Inc. Common Stock (PRME) short interest & short volume · 32.9M shares short
Prime Medicine, Inc. Common Stock official short interest (FINRA, twice monthly) and daily short volume (FINRA Reg SHO), with history, % of float and days to cover.
What changed
PRME short interest rose 2.4% to 32.9M shares in the Oct 15, 2026 report (5.5 days to cover). Daily short volume averaged 56.1% of volume over the last 20 sessions, up from 54.4% the 20 sessions before, the 41st percentile of its own 20-day averages since Sep 23, 2025.
Short interest
Official, twice monthly · settled Oct 15, 2026
- Shares short
- 32.9M
- prior 32.1M
- % of float
- —
- no float on file
- Days to cover
- 5.5
- avg vol 6.0M
- Change vs prior report
- +2.4%
Days to cover is short interest divided by FINRA's average daily volume for the period: how many average days of trading it would take shorts to buy back.
Source: FINRA equity short interest (twice monthly) · Settlement Oct 15, 2026
Daily short volume
Share of each day's volume sold short · FINRA Reg SHO
- Latest (Nov 2)
- 56.2%
- 971K of 1.7M
- 20-day average
- 56.1%
- prior 54.4%
- Percentile vs own history
- 41st
- 233 periods since 2025
Loading prices…
Source: FINRA Reg SHO daily short sale volume · Latest Nov 2, 2026
Short squeeze score (model)
Price since settlement: +26.0%
Model, not a forecast: 40 pts short interest % of float (full at 30%), 25 pts days to cover (full at 10), 15 pts rise in short interest since the prior report (full at +50%), 20 pts price gain since the settlement date (full at +25%). Missing inputs score 0.
PRME's squeeze score and its inputs with Lician Pro.Start 3-day trial — $149/yr
Market-wide: most shorted stocks, biggest changes and unusual short volume · PRME overview
| Date | Short | Total | Short % of volume |
|---|---|---|---|
| 2026-11-02 | 971,419 | 1,728,192 | 56.2% |
| 2026-10-30 | 1,227,042 | 3,014,085 | 40.7% |
| 2026-10-29 | 2,168,131 | 5,333,764 | 40.6% |
| 2026-10-28 | 3,697,262 | 7,042,157 | 52.5% |
| 2026-10-27 | 2,237,944 | 4,808,876 | 46.5% |
| 2026-10-26 | 768,409 | 1,253,351 | 61.3% |
| 2026-10-23 | 1,377,040 | 2,487,583 | 55.4% |
| 2026-10-22 | 741,173 | 1,305,202 | 56.8% |
| 2026-10-21 | 491,806 | 909,917 | 54.0% |
| 2026-10-20 | 727,875 | 1,405,916 | 51.8% |
Healthcare peers with similar quant ratings
PRME is rated 1.85 of 5 among 532 rated Healthcare stocks (Lician quant rating, Nov 4, 2026). How the rating works
- CDXS short interest1.88 · Sell · stock
- TRVI short interest1.87 · Sell · stock
- QDEL short interest1.86 · Sell · stock
- CTMX short interest1.85 · Sell · stock
- SIGA short interest1.84 · Sell · stock
- BCAX short interest1.83 · Sell · stock
- BDTX short interest1.82 · Sell · stock
- CUE short interest1.82 · Sell · stock
PRME short interest FAQ
What is PRME's short interest?
Prime Medicine, Inc. Common Stock (PRME) had 32.9M shares sold short and not yet covered in FINRA's Oct 15, 2026 settlement report.
How many days to cover does PRME have?
5.5 days: 32.9M shares short divided by an average daily volume of 6.0M for the Oct 15, 2026 period.
Is PRME short interest rising or falling?
PRME short interest rose (+2.4%) from 32.1M to 32.9M shares in the Oct 15, 2026 report.
Is PRME a short squeeze candidate?
Lician's squeeze watch scores PRME 35 out of 100 (low) from the Oct 15, 2026 report: days to cover 13.8/25, change in short interest vs prior report 0.7/15, price change since settlement date 20/20. It is a transparent model of how crowded the short side is, not a forecast that a squeeze will happen.
What share of PRME daily volume is sold short?
56.1% on average over the last 20 sessions to Nov 2, 2026 (FINRA Reg SHO daily short volume; the 41st percentile of its own 20-day averages). Short volume counts market makers' same-day short sales, so it is not short interest.
What was PRME's latest FINRA short volume?
On Nov 2, 2026, cached FINRA short volume for Prime Medicine, Inc. Common Stock (PRME) was 971,419 shares, 56.2% of 1,728,192 total volume.
How many PRME short-volume sessions are listed on this page?
This page lists 10 cached FINRA short-volume sessions for Prime Medicine, Inc. Common Stock (PRME), from Oct 20, 2026 through Nov 2, 2026.
How did PRME short volume percent change from the prior cached session?
Cached FINRA short volume for Prime Medicine, Inc. Common Stock (PRME) moved from 40.7% on Oct 30, 2026 to 56.2% on Nov 2, 2026, up 15.5 percentage points.
Not investment advice. Figures as filed or reported, not a live feed.