ISRG vs MSFT: Which Stock is Better?

Side-by-side comparison of Intuitive Surgical Inc and Microsoft Corporation in 2026

Comparison Updated:

ISRG

Intuitive Surgical Inc

$572.75

MSFT

Microsoft Corporation

$477.18

Key Metrics Comparison

MetricISRGMSFTWinner
Market Cap$210.15B$3.56TMSFT
P/E Ratio77.5534.14MSFT
EPS (TTM)$7.56$14.04MSFT
Revenue Growth0.2%0.2%ISRG
Gross Margin66.4%68.8%MSFT

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Frequently Asked Questions

Is ISRG or MSFT a better investment?

Comparing ISRG and MSFT: Intuitive Surgical Inc has a market cap of $210.15B while Microsoft Corporation has $3.56T. Both companies have their strengths - use our detailed metrics comparison to make an informed decision.

What is the difference between ISRG and MSFT?

ISRG (Intuitive Surgical Inc) and MSFT (Microsoft Corporation) differ in valuation, growth rates, and profitability metrics. Our comparison shows which company leads in each category.

Which stock has better value: ISRG or MSFT?

Based on P/E ratios, MSFT trades at a lower multiple (34.1x vs 77.5x).

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